Audax Italiano vs Colo Colo

This Copa Chile Round of 16 tie matters: the winner meets Ñublense or Puerto Montt in the quarterfinals, with the eventual champion earning a 2027 Copa Libertadores spot. Colo Colo sit top of the Liga de Primera with 42 points from 17 games, while Audax Italiano languish in the lower half, making this a big test for the underdogs. Colo Colo won their group behind a 3-0 rout of Unión Española, though a 0-0 draw with Huachipato has since cooled their league form. Audax advanced as runners-up and arrive off a 1-0 win at Deportes Concepción. Javier Correa leads Colo Colo's attack, while Audax will look to new signing Diego Coelho, who scored 12 goals last season at Cobresal. In Copa Chile specifically, Colo Colo have dominated, winning 18 of the last 25 meetings. Expect Colo Colo's superior form and squad depth to tell across the tie, even if Audax's new-look attack asks some questions early on. Our prediction: 2-0